The
infraNET Project and
Waterloo Institute for Health Informatics Research
University of Waterloo
present ...
Personalized Medicine : Today
and Tomorrow
by
Dr. Richard Kim
Professor of
Medicine and Physiology & Pharmacology,
Scientist, Lawson Health Research Institute,
Chair, Division of Clinical Pharmacology,
Director, Centre for Clinical Investigation & Therapeutics
University of Western Ontario
Wednesday,
February 27, 2008
3:00 p.m. - 4:30 p.m.
Davis Centre, Room 1302
University of Waterloo
Seminar Series Sponsors
Borden Ladner Gervais LLP
McKesson Information Solutions - Smart Systems for Health Agency
Healthcare Information Management and Communications Canada
Abstract
Unexpected withdrawal or health warnings for drugs such as
tegaserod (Zelnorm) and rosiglitazone (Avandia) continue to point to
deficiencies in the way new drugs are tested and studied in our
patients. Personalized Medicine represents the integration of data
about a patient s genetic makeup, specifically Single Nucleotide
Polymorphisms (SNPs) in the genes that affect drug disposition or response,
together with that of dietary and environmental influences and the patient
s clinical or disease state, to identify treatment options more
tailored to an individual patient. The hope is to move from iterative
drug and dose selection to the individualization of drug therapies
based on a predictive model of a patient s ability to handle and
respond to drugs. Systematic integration of Omics technologies
(genomics, transcriptomics, proteomics, and metabolomics) along with
information management systems will be crucial to realizing the promise
of individualized patient therapy.
About the Speaker
Dr. Kim received his MD from the U. of Saskatchewan in
1987. After his internship and residency training in Internal Medicine
at the Royal University Hospital in Saskatoon in 1991, he did a postdoctoral
fellowship in Clinical Pharmacology at Vanderbilt University. On completion
of his fellowship in 1994, he remained at Vanderbilt University School
of Medicine as a faculty member. In 2006, he moved his group to the University
of Western Ontario. He is currently Professor and Chair of the Division
of Clinical Pharmacology in the Department of Medicine and Director of the
Centre for Clinical Investigation & Therapeutics. His research
interest is in understanding the molecular basis of interindividual
differences in drug disposition with application to Personalized Medicine.
For more information
Shirley Fenton
Managing Director, WIHIR
University of Waterloo
(519) 888-4074
Seminar Hosts
This seminar is hosted by the Waterloo Institute for Health
Informatics Research (WIHIR) and The infraNET Project, University of Waterloo.
The infraNET Project, initiated by the University of Waterloo in
1996, is a partnership to advance Web and Internet technologies. Its founding
partners were: LivePage (now part of Oracle), MKS, Open Text, RIM,
Sybase (Waterloo) and Waterloo Maple.
We also gratefully acknowledge the assistance of the Institute for
Computer Research, University of Waterloo.
